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purepep chorus peptide synthesizer  (Gyros Protein Technologies)


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    Structured Review

    Gyros Protein Technologies purepep chorus peptide synthesizer
    Purepep Chorus Peptide Synthesizer, supplied by Gyros Protein Technologies, used in various techniques. Bioz Stars score: 95/100, based on 82 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/purepep+chorus+peptide+synthesizer/PurePep+Chorus/pmc13125359-246-14-18
    Average 95 stars, based on 82 article reviews
    purepep chorus peptide synthesizer - by Bioz Stars, 2026-09
    95/100 stars

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    other:

    Article Title: Selenalysine as a Chemical Tool for Probing Histone Post-Translational Modifications.
    Article Snippet: Post-translational modifications (PTMs) on histones play a crucial role in determining the structure and function of chromatin, thereby regulating the eukaryotic gene expression.. Histone lysine methylation and acetylation are among the most widespread and biomedically important PTMs, with new chemical tools for their examination in high demand.. Here, we report the first use of γ-selenalysine as an efficient lysine mimic for enzymatic methylation, acetylation, and deacetylation reactions catalyzed by histone lysine methyltransferases, acetyltransferases, and a deacetylase.

    Article Title: Exploring Multivalency in the Development of Anti-PD-L1 Peptides for Cancer Immunotherapy.
    Article Snippet: Purpose The PD-1/PD-L1 pathway is one of the most effective immune checkpoint pathways utilized for cancer immunotherapy.. Despite the success of anti-PD-1/PD-L1 mAbs, there is growing interest in developing low molecular weight anti-PD-1/PD-1 agents, such as peptides, because of their improved tumor penetration.. We recently developed a small antiPD-L1 peptide and demonstrated its promising anti-tumor activity.

    Synthesized:

    Article Title: Improvement of Analysis and Transferability in Peptide Purification: From HPLC to FPLC and Back Again.
    Article Snippet: .. All peptides listed in Table 1 were individually synthesized via standard Fmoc solid- phase peptide synthesis (SPPS) using a PurePep Chorus peptide synthesizer (Gyros Protein Technologies, Warren, NJ, United States). ..

    Article Title: Improvement of Analysis and Transferability in Peptide Purification: From HPLC to FPLC and Back Again
    Article Snippet: .. All peptides listed in Table were individually synthesized via standard Fmoc solid‐phase peptide synthesis (SPPS) using a PurePep Chorus peptide synthesizer (Gyros Protein Technologies, Warren, NJ, United States). ..

    Article Title: De novo design of high-affinity binders of bioactive helical peptides
    Article Snippet: .. The TAMRA-Bid peptide was synthesized using a PurePep Chorus peptide synthesizer (Gyros Protein Technologies). .. Fmoc-protected amino acids were purchased from Ambeed.

    Article Title: Collagen hybridizing peptide imaging and delivery of therapeutic antibody in rheumatoid arthritis models.
    Article Snippet: .. As described in our previous reports, peptides were synthesized on a Rink Amide-AM resin (HECHENG, loading: 0.37 mmol/g) with standard Fmoc-chemistry solid-phase synthesis using a PurePep Chorus peptide synthesizer (Gyros Protein Technologies). .. The peptides were fluorescently labeled with the N-hydroxysuccinimide (NHS) ester of either sulfo-Cyanine 3 (Cy3, Lumiprobe, 41320) or sulfo-Cyanine 7 (Cy7, Lumiprobe, 25320) on resin before cleavage and purified by reverse phase high-performance liquid chromatography (RP-HPLC) on a semi-preparative column (Agilent ZORBAX StableBond 300 C18) using a mixture of H2O (0.1% TFA, v/v) and acetonitrile (0.1% TFA, v/v) as the mobile phase (4 mL/min).

    Article Title: Substrate selectivity of human histidine methyltransferase METTL9
    Article Snippet: .. All the SLC39A5 peptides were synthesized on the Rink amide resin using an automated PurePep Chorus peptide synthesizer (Gyros Protein Technologies). ..

    Article Title: Delineating, Imaging, and Assessing Pulmonary Fibrosis Remodeling via Collagen Hybridization.
    Article Snippet: Idiopathic pulmonary fibrosis (IPF) is a progressive, life-threatening disease with no early detection, few treatments, and dismal outcomes.. Although collagen overdeposition is a hallmark of lung fibrosis, current research mostly focuses on the cellular aspect, leaving collagen, particularly its dynamic remodeling (i.e., degradation and turnover), largely unexplored.. Here, using a collagen hybridizing peptide (CHP) that specifically binds unfolded collagen chains, we reveal vast collagen denaturation in human IPF lungs and delineate the spatiotemporal progression of collagen denaturation threedimensionally within fibrotic lungs in mice.



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